Serum: Toxic Survival

First-person survival against mutants, toxic fog, and a ticking clock

Game Island · Published by Toplitz Productions · Released May 23, 2024 · Early Access

As of Oct 28, 2026: Early Access, no updates for over a year AI-generated content disclosed

Reviews: Mixed; 48% of 267
Recent reviews: Not enough recent
Players: 0; daily peak, Oct 28, 2026
Steam Deck: Unsupported
Last update on Steam: 2 years ago; Sep 18, 2024
Minimum PC: GeForce GTX 1070; 12 GB RAM · 15 GB disk; Full requirements

What is Serum: Toxic Survival?

This single-player, first-person survival game takes place on a ruined island as you investigate the serum and search for a way out. You explore different biomes, gather resources from plants and animals, brew mixtures that alter your abilities, and craft tools, traps, and weapons to fight mutated creatures.

For you if...

+you like preparing supplies before venturing into hostile territory
+you enjoy balancing ability boosts against potentially harmful side effects

Not for you if...

−you prefer exploring without a survival countdown
−you want cooperative survival rather than playing alone

What players say

48% of 267 reviews are positive

Players praise the setting and serum-based survival concept. Recent reviewers describe development as abandoned and criticize the lack of updates and communication. Players also report bugs and poor performance.

Screenshots and trailer

Serum: Toxic Survival system requirements

Minimum: GeForce GTX 1070, 12 GB RAM, 15 GB of disk space.

As published by the developer.

Can my PC run Serum: Toxic Survival?

Tell us your graphics card once and every game page will answer this for you.

Set up my PC →

Minimum

OS: Windows 10 (x64)
Processor: Intel Core i5-8400 or AMD Ryzen 5 2600X
Graphics: NVIDIA GeForce GTX 1070, 8 GB or AMD Radeon RX Vega 56, 8 GB or Intel Arc A750, 8 GB
Memory: 12 GB RAM
Storage: 15 GB available space
DirectX: Version 11
Notes: Low settings, 1080p @ 30 FPS. CPU must support at least the SSE3 instruction set. Does not require the AVX instruction set.

OS: Windows 10 (x64)
Processor: Intel Core i5-10400 or AMD Ryzen 5 3600X
Graphics: NVIDIA GeForce RTX 3060 Ti, 8 GB or AMD Radeon RX 6600 XT, 8 GB
Memory: 16 GB RAM
Storage: 15 GB available space
DirectX: Version 11
Notes: High settings, 1080p @ 60 FPS. CPU must support at least the SSE3 instruction set. Does not require the AVX instruction set.

Does Serum: Toxic Survival have co-op or multiplayer?

No: single-player only, no multiplayer modes declared.

Single-player

Does Serum: Toxic Survival run on Steam Deck?

Unsupported No: Valve rates it Unsupported on Steam Deck.

Not supported on SteamOS

PC version details

DRM: None declared on Steam
Controller: Full controller support
Platforms: Windows
Achievements: 23
Steam features: Family Sharing
Languages: Full audio: English. Text only: French, German, Spanish - Spain, Polish, Turkish, Russian, Ukrainian, Portuguese - Brazil, Simplified Chinese, Japanese, Korean.

Does Serum: Toxic Survival use AI-generated content?

Yes. The developers disclose AI-generated content on the game's Steam page:

The game is using the AI-generated prompts in audio form.

Self-reported by the developer under Steam rules: it covers AI content that ships in the game, not tools used to make it. Steam page checked on Oct 27, 2026. How to filter AI games on Steam