PCGame

Chromosome Evil 2

Top-down survival strategy with squad combat and convoy management

S.C. 16 BIT NIGHTS S.R.L., dovganovskiy · Published by S.C. 16 BIT NIGHTS S.R.L. · Released Feb 15, 2024

RPGStrategy

Reviews
Very Positive
88% of 269
Recent reviews
Not enough recent
Playing now
1
right now
Steam Deck
Playable
Last update
7 months ago
Feb 17, 2026

Free demo available, 0 playing it now: get the demo.

What is Chromosome Evil 2?

A top-down, single-player strategy game set after a flesh organism brings down human governments. You command a military convoy, equip a strike team for real-time battles with an active-pause option, and assign personnel to survival tasks. The chapters progress from assembling the convoy to an open-world section with different paths and endings.

For you if...

  • +you like real-time squad tactics with an active pause
  • +you enjoy dark survival settings and resource planning
  • +you like choosing routes that lead to different endings

Not for you if...

  • you want constant combat without convoy logistics
  • you want fully turn-based battles rather than paused real-time combat

What players say

88% of 269 reviews are positive

Players praise the mix of squad tactics, survival horror, and crew management. Some find the pacing slow or repetitive, while opinions on the difficulty differ.

Screenshots and trailer

Chromosome Evil 2

Chromosome Evil 2 system requirements

As published by the developer.

Minimum

OS
Windows XP or higher
Processor
Pentium 4
Graphics
Any
Memory
8 GB RAM
Storage
1 GB available space
DirectX
Version 10

Recommended

OS
Windows 10
Processor
Multicore processors
Graphics
Any
Memory
16 GB RAM
Storage
2 GB available space
DirectX
Version 10

PC version details

DRM, required accounts, controller support and Steam features.

DRM
None declared on Steam
Controller
Keyboard and mouse
Platforms
Windows
Achievements
10
Steam features
Family Sharing, Trading cards

Steam Deck: Playable

  • Default controller config not fully functional
  • Sometimes shows mouse, keyboard or non-Deck controller icons
  • Some in-game text is small and may be hard to read
  • Default graphics settings perform well on Steam Deck

Multiplayer and co-op

Languages

Text only: English, Russian, Spanish - Latin America, Spanish - Spain, Simplified Chinese.

Tags

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