PCGame

Chromosome Evil 2

Top-down survival strategy with squad combat and convoy management

S.C. 16 BIT NIGHTS S.R.L., dovganovskiy · Published by S.C. 16 BIT NIGHTS S.R.L. · Released Feb 15, 2024

RPGStrategy

Reviews
Very Positive
83% of 259
Recent reviews
Not enough recent
Players
35
daily peak, Nov 7, 2026
Steam Deck
Playable
Last update on Steam
6 months ago
Apr 9, 2026
Minimum PC
Any
8 GB RAM · 1 GB disk
Full requirements

What is Chromosome Evil 2?

A top-down, single-player strategy game set after a flesh organism brings down human governments. You command a military convoy, equip a strike team for real-time battles with an active-pause option, and assign personnel to survival tasks. The chapters progress from assembling the convoy to an open-world section with different paths and endings.

For you if...

  • +you like real-time squad tactics with an active pause
  • +you enjoy dark survival settings and resource planning
  • +you like choosing routes that lead to different endings

Not for you if...

  • −you want constant combat without convoy logistics
  • −you want fully turn-based battles rather than paused real-time combat

What players say

83% of 259 reviews are positive

Players praise the mix of squad tactics, survival horror, and crew management. Some find the pacing slow or repetitive, while opinions on the difficulty differ.

Players over time

▲ +1120% vs a month ago

Players online on Steam, one sample a day.

Highest since Sep 2026: 35 players on Nov 7, 2026.

Show the data
DayPlayers
Nov 7, 202635
Nov 6, 202613
Nov 5, 20262
Nov 4, 20263
Nov 3, 20264
Nov 2, 20263
Nov 1, 20261
Oct 31, 20261
Oct 30, 20261
Oct 29, 20261
Oct 28, 20261
Oct 27, 20263
Oct 26, 20263
Oct 25, 20260
Oct 24, 20261
Oct 23, 20261
Oct 22, 20262
Oct 21, 20261
Oct 20, 20260
Oct 18, 20261
Oct 17, 20260
Oct 16, 20260
Oct 15, 20260
Oct 14, 20261
Oct 13, 20261
Oct 11, 20262
Oct 10, 20260
Oct 9, 20262
Oct 8, 20260
Oct 7, 20262
Oct 6, 20261
Oct 4, 20260
Oct 3, 20261
Oct 2, 20260
Oct 1, 20261
Sep 30, 20261
Sep 29, 20261
Sep 27, 20260
Sep 26, 20261
Sep 25, 20262
Sep 24, 20260
Sep 23, 20261
Sep 23, 20261
Sep 22, 20261

Screenshots and trailer

Chromosome Evil 2 screenshot 1

Chromosome Evil 2 system requirements

Minimum: Any, 8 GB RAM, 1 GB of disk space.

As published by the developer.

Can my PC run Chromosome Evil 2?

Tell us your graphics card once and every game page will answer this for you.

Set up my PC →

Minimum

OS
Windows XP or higher
Processor
Pentium 4
Graphics
Any
Memory
8 GB RAM
Storage
1 GB available space
DirectX
Version 10

Recommended

OS
Windows 10
Processor
Multicore processors
Graphics
Any
Memory
16 GB RAM
Storage
2 GB available space
DirectX
Version 10

Does Chromosome Evil 2 have co-op or multiplayer?

No: single-player only, no multiplayer modes declared.

Does Chromosome Evil 2 run on Steam Deck?

Playable Playable: it runs on Steam Deck with some adjustments.

  • Default controller config not fully functional
  • Sometimes shows mouse, keyboard or non-Deck controller icons
  • Some in-game text is small and may be hard to read
  • Default graphics settings perform well on Steam Deck

PC version details

DRM
None declared on Steam
Controller
Keyboard and mouse
Platforms
Windows
Achievements
10
Steam features
Family Sharing, Trading cards
Languages
Text only: English, Russian, Spanish - Latin America, Spanish - Spain, Simplified Chinese.

Does Chromosome Evil 2 use AI-generated content?

No AI-generated content is disclosed on the game's Steam page.

Self-reported by the developer under Steam rules: it covers AI content that ships in the game, not tools used to make it. Steam page checked on Oct 25, 2026. How to filter AI games on Steam

Tags

Recent updates

Games like Chromosome Evil 2