Genome Guardian
Top-down roguelite shooter with DNA-combined weapons and customizable turrets
Alpherior · Released May 7, 2024
- Reviews
- Very Positive
- 92% of 785
- Recent reviews
- Not enough recent
- Playing now
- 6
- right now
- Steam Deck
- Playable
- Last update
- 1 year ago
- Jul 21, 2025
Free demo available, 0 playing it now: get the demo.
What is Genome Guardian?
Genome Guardian is a top-down roguelite shooter set in a microscopic world, where you control a turret trying to survive attacks by microbes. Across short runs with different modes and depths, you combine DNA bases into weapons, choose perks and mods, and research permanent upgrades.
For you if...
- +you like experimenting with weapon combinations and turret builds
- +you enjoy fast-paced survival combat
- +you want short runs with new options to unlock
Not for you if...
- −you prefer long, continuous levels over short runs
- −you want a shooter with few upgrade decisions
What players say
92% of 785 reviews are positive
Players praise the variety of weapon combinations, turrets, and builds. Common complaints concern repetitive encounters, a cluttered interface, and projectiles that can be hard to tell apart during combat.
Screenshots and trailer
Genome Guardian system requirements
As published by the developer.
Minimum
- OS
- Windows 10
- Storage
- 800 MB available space
- Notes
- Change Quality / Render Scale in SETTINGS if low FPS
Recommended
- OS
- Windows 10
- Storage
- 800 MB available space
- Notes
- Change Quality / Render Scale in SETTINGS if low FPS
PC version details
DRM, required accounts, controller support and Steam features.
- DRM
- None declared on Steam
- Controller
- Full controller support
- Platforms
- Windows
- Achievements
- 100
- Steam features
- Cloud saves, Family Sharing, Trading cards
Steam Deck: Playable
- Sometimes shows mouse, keyboard or non-Deck controller icons
- Some in-game text is small and may be hard to read
- All functionality is accessible with the default controller configuration
- Default graphics settings perform well on Steam Deck
Tags
- Action Roguelike
- Shooter
- Roguelite
- Gun Customization
- Roguelike
- Top-Down Shooter
- Survival
- Science
- Atmospheric
- Colorful
- Aliens
- Bullet Hell
- Sci-fi
- Cute
- 2D
- Action
Recent updates
- Jul 21, 2025 · Update 7.0.4
- Jun 7, 2025 · Update 7.0.3
- May 24, 2025 · Update 7.0.2
- May 1, 2025 · Update 7.0.1
- Apr 1, 2025 · Update 7.0.0: 🃏🃏🃏ThE jEsTeR uPdAtE🃏🃏🃏
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