Best Science games on PC
These games use real or fictional science as a central subject, setting, or system, including physics, space, evolution, engineering, and laboratory research. Players may solve puzzles, run simulations, build systems, or survive in research environments.
- Scientific themes and settings
- Simulation, puzzles, or survival
- Physics, engineering, and experimentation
Related: Simulation, Physics, Space, Sci-fi
414 games on PC, with requirements, reviews and prices.
414 games
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Odyssey - The Story of Science
Island puzzle adventure teaching the history of astronomy and physics
75% positive
209 reviews
The King's Request: Physiology and Anatomy Revision Game
An adventure RPG with anatomy and physiology quiz battles
94% positive
Free
Comet 64
Programming puzzles solved by coding on a retro home computer
75% positive
199 reviews
Lazy Galaxy
Idle strategy with base building and real-time space battles
79% positive
197 reviews
Biotope
Aquarium management simulator built around fish care and water chemistry
41% positive
196 reviews
P·O·L·L·E·N
First-person sci-fi mystery inside a research base on Titan
62% positive
191 reviews
Prime Mover
Open-ended programming puzzles with circuit boards nested inside each other
86% positive
191 reviews
法医探案团之碎嘴小诗
FMV mystery adventure where you investigate your own death
81% positive
188 reviews
Noise
First-person horror adventure about tracing a mysterious radio signal
56% positive
187 reviews
Project Third Eye
VR physics sandbox where you program how objects behave
73% positive
187 reviews
Mechanic Miner
Physics-based survival sandbox about building and using steam-powered machines
56% positive
185 reviews
Titans of Space PLUS
Educational space tour comparing the sizes of planets and stars
93% positive
183 reviews
Looking For Fael
First-person puzzle adventure through a maze of interconnected apartments
98% positive
182 reviews
Project Chemistry
A chemistry simulation for examining molecules and testing reactions
84% positive
176 reviews
Size Matters
First-person laboratory puzzles with a shrinking scientist racing against time
91% positive
174 reviews
Rocket Science
Rocket-building sandbox simulation set in a full-scale Solar System
77% positive
172 reviews
Evil Mansion
First-person social deduction with hidden killers in a former cult mansion
77% positive
Free
ANLIFE: Motion-Learning Life Evolution
Physics-based evolution sandbox where block creatures learn to move
84% positive
171 reviews
Emergency Room Simulator
First-person medical simulator about diagnosing and treating emergency room patients
42% positive
170 reviews
Idle Monkeylogy
An idle clicker where monkeys type random letters into words
59% positive
Free
malViolence - Definitive Edition
Puzzle-focused visual novel about escaping a supervillain's deadly tests
93% positive
Free
Life Below
An underwater city builder focused on restoring damaged marine ecosystems
78% positive
166 reviews
Colorgrid
A logic puzzle game about mixing colors with lasers
90% positive
163 reviews
Demo Cell Command
Turn-based tactics where moving grows your cells and attacking shrinks them
97% positive
162 reviews