PCGame

Best Science games on PC

These games use real or fictional science as a central subject, setting, or system, including physics, space, evolution, engineering, and laboratory research. Players may solve puzzles, run simulations, build systems, or survive in research environments.

Related: Simulation, Physics, Space, Sci-fi

414 games on PC, with requirements, reviews and prices.

414 games

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Growing My Grandpa!
Growing My Grandpa!
Point-and-click horror about raising a strange creature in a basement
98% positive 490 reviews
Tyto Ecology
Tyto Ecology
Ecology sandbox about building and balancing a living biodome
74% positive 470 reviews
Base One
Base One
Space station management with specialized crews and shared survival resources
38% positive 470 reviews
Zombie Cure Lab
Zombie Cure Lab
Colony management sim about curing zombies and defending your lab
68% positive 467 reviews
InMind VR
InMind VR
VR arcade ride through the brain with gaze-based targeting
78% positive Free
Evolution Board Game
Evolution Board Game
Turn-based board game about adapting species with trait cards
84% positive 450 reviews
Nuclear Design Bureau AI
Nuclear Design Bureau
Engineering sandbox for designing nuclear devices under technical constraints
77% positive 448 reviews
Atomcraft Demo AI
Atomcraft
A chemistry sandbox where every pixel can be moved
95% positive 445 reviews
Who Wants To Be A Millionaire
Who Wants To Be A Millionaire
TV quiz game with escalating questions and a prize ladder
52% positive 440 reviews
HyperRogue
HyperRogue
Turn-based puzzle roguelike set in a world of warped geometry
97% positive 431 reviews
Interstellar Transport Company
Interstellar Transport Company
Space business simulation about supplying colonies and managing trade routes
67% positive 416 reviews
My Little Spider
My Little Spider
Idle desktop companion with a spider that collects insects
94% positive 416 reviews
1000 days to escape
1000 days to escape
Space arcade simulation about evacuating Earth before oxygen runs out
85% positive 413 reviews
Tornado: Research and Rescue
Tornado: Research and Rescue
Open-world storm-chasing simulation combining weather research with rescue work
85% positive 410 reviews
Rover Mechanic Simulator
Rover Mechanic Simulator
A mechanic simulator about restoring research rovers on Mars
83% positive 397 reviews
JOY OF PROGRAMMING - Software Engineering Simulator
JOY OF PROGRAMMING - Software Engineering Simulator
3D programming puzzles where Python code controls machines and robots
77% positive 396 reviews
Intergalactic Fishing
Intergalactic Fishing
Fishing simulation across the universe with procedurally generated lakes
95% positive 395 reviews
Reactor Tech²
Reactor Tech²
Power-plant management simulation about balancing fuel, water, and electrical output
67% positive 395 reviews
Bombe Demo
Bombe
Minesweeper-style puzzle game where your rules automate future solutions
95% positive 388 reviews
THE MULLER-POWELL PRINCIPLE: Director's Cut
THE MULLER-POWELL PRINCIPLE: Director's Cut
First-person sci-fi puzzle adventure built around absorbing and redirecting energy
73% positive 383 reviews
Logic World
Logic World
First-person circuit-building sandbox where logic gates become working machines
94% positive 369 reviews
Lab Rat
Lab Rat
A box-pushing puzzle game supervised by a metrics-obsessed AI
97% positive 367 reviews
Message From Aliens Demo
Message From Aliens
A sci-fi puzzle game about decoding an alien writing system
96% positive 360 reviews
The Dream Of A Cockspur AI
The Dream Of A Cockspur
Surreal point-and-click horror about researchers stranded on an island
94% positive 356 reviews